Toward the Characterization of Peptidoglycan Structure and Protein−Peptidoglycan Interactions by Solid-State NMR Spectroscopy
Thomas Kern, Sabine Hediger,Patrick Müller,§ Cécile Giustini, Bernard Joris, Catherine Bougault,Waldemar Vollmer, and Jean-Pierre Simorre
Abstract:
Solid-state NMR spectroscopy is applied to intact peptidoglycan sacculi of the Gram-negative bacterium Escherichia coli. High-quality solid-state NMR spectra allow atom-resolved investigation of the peptidoglycan structure and dynamics as well as the study of protein−peptidoglycan interactions.
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