Angewandte Update from Jan. 07 - Present

Secondary Structure, Dynamics, and Topology of a Seven-Helix Receptor in Native Membranes, Studied by Solid-State NMR Spectroscopy
Manuel Etzkorn, Swetlana Martell, Ovidiu C. Andronesi, Karsten Seidel, Martin Engelhard, Marc Baldus
Angewandte (2007) 46, 459.

Summary:
In the loop: High-resolution solid-state NMR spectroscopy is used to study the secondary structure, dynamics, and membrane topology of an entire seven-helix receptor, sensory rhodopsin II from Natronomonas pharaonis. The experiments are carried out on a single isotope-labeled sample in a native membrane environment.


Solid-State NMR Spectroscopy of a Paramagnetic Protein: Assignment and Study of Human Dimeric Oxidized CuII-ZnII Superoxide Dismutase (SOD)
Guido Pintacuda, Nicolas Giraud, Roberta Pierattelli, Anja Böckmann, Ivano Bertini, Lyndon Emsley
Angewandte (2007)46,1079.

Summary:
A solid story: The paramagnetic form of the protein superoxide dismutase (SOD; see portion of structure in upper right corner of picture with detectability sphere in blue) is shown to be accessible to high-resolution solid-state magic angle spinning NMR studies when in microcrystalline form. A nearly complete assignment of the signals of this 32-kDa dimer has been achieved.