Friday, September 01, 2006

Prog. in NMR: platinum anti-cancer drugs and 195Pt NMR - Review article

Review article
Progress in Nuclear Magnetic Resonance Spectroscopy
Volume 49, Issue 1 , 15 August 2006, Pages 65-98

Insights into the mechanism of action of platinum anticancer drugs from multinuclear NMR spectroscopy

Susan J. Berners-Price, Luca Ronconi and Peter J. Sadler

School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Crawley, Perth, WA 6009, Australia
School of Chemistry, University of Edinburgh, West Mains Road, Edinburgh EH9 3JJ, UK

Keywords: NMR; Platinum drugs; 195Pt NMR; 15N NMR; [1H,15N] NMR; Proteins; Glutathione; DNA; Aquation; Kinetics

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